The unreasonable redundancy of nature’s protein folds

Natural protein sequence space contains enough fold redundancy that generating more sequences is often less useful than understanding which folded structures are actually distinct

Today, we are launching our research blog! We’ll use it for technical notes from our work building tools for enzyme and biomolecular design. Our first post is about The Unreasonable Redundancy of Nature's Protein Folds. TLDR: Please do
Ranked #10 on backlist 2026-06-03 (03 Jun 2026 UTC) · by (Arda Göreci) ·

How it ranks: Backlist reads my Twitter/X timeline, scores every tweet for substance with an LLM rubric (not engagement), and publishes the daily top picks with a one-line takeaway. Curated by Surya Dantuluri.